Treatment Strategy for Hyperammonemia in Lung Transplantation

Idiopathic Hyperammonemia after Orthotopic Lung Transplantation

Idiopathic hyperammonemia is characterized by increased serum ammonia levels (>200umol/L) and is sometimes associated with normal to slightly elevated liver function tests [1]. These patients often present with encephalopathy, cerebral edema, seizures, and coma. Idiopathic hyperammonemia has been reported after high dose chemotherapy, and organ transplants including Orthotopic lung transplant [...

Neural Transplantation as a Strategy for Recovery of CNS Functions

Transplants of neural tissue have been used for nearly 100 years in order to clarify the mechanisms that underlie development and regeneration of the nervous system. With reports from Sweden and Mexico that autografts of adrenal medulla produce at least transient and perhaps dramatic improve­ment in patients severly disabled by Parkinson's disease, the techniques of neural transplantation have ...

Lung protection strategy as an effective treatment in acute respiratory distress syndrome

Lung protection strategy as an effective treatment in acute respiratory distress syndrome

A new treatment strategy for advanced idiopathic interstitial pneumonia: living-donor lobar lung transplantation.

BACKGROUND Among patients awaiting cadaveric lung transplantation, patients with idiopathic interstitial pneumonia (IIP) have been demonstrated to have the highest mortality rate. Contraindications to cadaveric lung transplantation include current high-dose systemic corticosteroid therapy because it may increase airway complications and various types of infection. STUDY OBJECTIVES To analyze ...

Lung Transplantation: Advances and Roadblocks in Treatment